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75g oral glucose tolerance test (OGTT) values — enter what's available.

mg/dL
mg/dL
mg/dL

How it's calculated

Under the IADPSG/WHO one-step approach, gestational diabetes is diagnosed if the value at any single timepoint of a 75g OGTT meets or exceeds its threshold — no second confirmatory test is required.

Diagnostic thresholds

TimepointThreshold
Fasting≥92 mg/dL (5.1 mmol/L)
1-hour≥180 mg/dL (10.0 mmol/L)
2-hour≥153 mg/dL (8.5 mmol/L)

Clinical use

Frequently asked questions

How many abnormal OGTT values are needed to diagnose GDM?

Under IADPSG/WHO one-step criteria, just one abnormal value (fasting, 1-hour, or 2-hour) meeting or exceeding its threshold is sufficient to diagnose gestational diabetes.

What's the difference between the one-step and two-step approach?

The one-step approach (used here) is a single 75g OGTT with IADPSG/WHO thresholds. The two-step approach first uses a 50g glucose challenge test as a screen, then a confirmatory 100g OGTT with Carpenter-Coustan criteria only if the screen is positive. Both are used internationally; check local/institutional protocol.

When is GDM screening usually done?

Typically at 24-28 weeks' gestation for most pregnant women, though those with risk factors (e.g. obesity, prior GDM, strong family history) are often screened earlier as well.

References

  1. International Association of Diabetes and Pregnancy Study Groups (IADPSG) Consensus Panel. Recommendations on the diagnosis and classification of hyperglycemia in pregnancy. Diabetes Care. 2010;33:676-682.
  2. World Health Organization. Diagnostic Criteria and Classification of Hyperglycaemia First Detected in Pregnancy. 2013.

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